Buffalo Chicken Casserole

This buffalo chicken casserole is easy, healthy, and so flavorful! The chicken is hearty and tender. The sauce is thick and creamy. Make this casserole for a nutritious family dinner, game day appetizer, or meal prep!
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This buffalo chicken casserole is loaded with flavor! It is an easy and healthy recipe for family dinners, game day appetizers, and meal prep. The chicken is tender and hearty, while the sauce is thick and creamy. Kids and adults love this chicken casserole!

Buffalo chicken casserole.

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Why You’ll Love This Recipe

  • This buffalo chicken casserole is quick and easy to make!
  • Great for meal prep and leftovers.
  • Everything comes together easily.
  • Check out more Chicken Meal Prep Ideas and Chicken Breast Recipes!
  • The buffalo chicken flavor is strong and delicious!
  • Bring this dish to a game day party or potluck.
  • Kids and picky eaters love it too!
  • Check out this Chicken Casserole for another great dinner recipe.

Ingredients & Substitutes

These are the ingredients and substitutes for this buffalo chicken casserole. Scroll down to the recipe card below for the entire recipe.

Use cooked, shredded chicken. This recipe is a great way to use up leftover chicken.

Use cooked, shredded spaghetti squash. If needed, replace with cooked and drained whole wheat pasta.

Buffalo sauce adds a spicy flavor and creamy texture. For a more spicy flavor, use regular hot sauce.

Shredded cheese adds a delicious cheesy flavor and texture! We love mozzarella for this recipe.

The egg helps bind everything together.

Add flavor with garlic powder, onion powder, paprika, and black pepper.

Ingredients for buffalo chicken casserole.

Taste & Texture

This buffalo chicken casserole is a little spicy, cheesy, and so flavorful. It tastes very similar to buffalo chicken dip.

The chicken is tender and juicy. Overall, this casserole is creamy and delicious!

How to Make

Step 1

First, preheat the oven to 400 degrees Fahrenheit.  Lightly spray a baking dish with nonstick spray.

Step 2

Combine all of the ingredients in a mixing bowl.  Mix until combined.

Step 3

Transfer this mixture to the greased baking dish.

Baking dish with hot sauce and chicken.

Step 4

Bake for 20 to 25 minutes or until the edges are bubbly.

Baked casserole with spicy chicken.

Step 5

Finally, remove from the oven.  Serve hot!

Expert Tips for Success

Follow these tips and tricks to make the best buffalo chicken casserole!

First, use cooked and shredded chicken.

Bake until the casserole is bubbly around the edges.

Flavor Variations & Add-Ins

The beauty of this casserole is that it is incredibly versatile. Feel free to get creative and add your own personal touch! Here are a few ideas:

Add extra cheese to the sauce or sprinkle on some shredded cheddar or Monterey Jack before baking. We also love mozzarella cheese!

Throw in some chopped broccoli, cauliflower, or spinach for an extra dose of nutrients.

Add a chipotle pepper to the sauce for a smoky flavor twist.

Add some chopped peppers and onions for added flavor.

Close up of buffalo chicken casserole.

How to Serve & Store

This buffalo chicken casserole is perfect for a main course, but it can also be served as a side dish.

Pair it with mashed potatoes, roasted vegetables, or a simple salad.

Store leftovers in an airtight container in the refrigerator for up to 4 days. Reheat gently in the oven or microwave.

Frequently Asked Questions (FAQs)

Can I prepare this casserole ahead of time?

Absolutely! You can assemble the casserole in advance and pop it in the fridge until you’re ready to bake it. Keep in mind that it may take a bit longer to cook since it’s coming straight from the fridge.

Does this casserole recipe work with regular pasta?

If needed, use regular pasta. We recommend whole wheat pasta.

Can I use a different type of cheese?

Absolutely! Go ahead and experiment with different cheeses. Cheddar, pepper jack, or even a mix of cheeses will all work well and add their own unique flavor.

What should I serve with this casserole?

While the Buffalo Chicken Casserole is a complete meal on its own, you can pair it with a side of coleslaw or a crisp green salad for a well-rounded dinner.

Equipment Needed

Pyrex 3 Glass Mixing Bowls: Mix everything in one of these mixing bowls.

Staub Baking Dishes: We love these dishes for casseroles.

Check out all of our Kitchen Favorites!

Spaghetti squash with spicy chicken.

You May Also Enjoy

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